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Dephostatin, a novel protein tyrosine phosphatase inhibitor produced by Streptomyces. II. Structure determination
H Kakeya1, M Imoto, Y Takahashi
1Department of Applied Chemistry, Faculty of Science and Technology, Keio University, Yokohama, Japan.
The Journal of Antibiotics
|November 1, 1993
Abstract:
Dephostatin, a novel tyrosine phosphatase inhibitor, was isolated from the culture broth of Streptomyces sp. MJ742-NF5. The structure was elucidated to be 2-(N-methyl-N-nitroso)hydroquinone by spectral and chemical analyses of dephostatin and its derivatives.