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Related Experiment Videos

Lung function in workers refining phosphorus rock to obtain elementary phosphorus

C B Dutton1, M J Pigeon, P M Renzi

  • 1Albany Medical College, New York 12208.

Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association
|October 1, 1993
PubMed
Summary

Industrial refinery air pollutants like phosphoric acid and fluorides did not significantly impact worker lung function. Smoking remains the primary factor in reduced spirometry, with no adverse effects observed in exposed non-smokers.

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Area of Science:

  • Occupational Health
  • Pulmonary Medicine
  • Environmental Science

Background:

  • Workplace air in an industrial refinery contained elevated levels of phosphoric acid, phosphorus pentoxide, fluorides, and coal tar pitch volatiles.
  • Previous studies have documented the negative impact of smoking on lung function.

Purpose of the Study:

  • To investigate the longitudinal and cross-sectional effects of industrial refinery air pollutants on worker pulmonary function.
  • To determine if industrial exposure contributes to lung function decline independently of age and smoking status.

Main Methods:

  • Prospective annual pulmonary function testing (spirometry) was conducted on 131 refinery workers over 3 to 7 years.
  • Regression analysis was used to analyze spirometric data, adjusting for age and smoking.

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  • Comparison of lung function between exposed workers, non-smokers, and former smokers.

    • Main Results:

    • No significant residual effect of industrial exposure on spirometric lung function was found after adjusting for age and smoking.
    • Industrial exposure contributed only weakly and inconsistently to lung function reduction compared to smoking.
    • Exposed non-smokers and former smokers showed no significant reductions in spirometry.

    Conclusions:

    • Occupational exposure to the studied refinery air pollutants does not appear to cause significant long-term lung function impairment.
    • Smoking remains the dominant factor in reduced spirometric lung function among workers.
    • Further research may be warranted to explore potential subtle or long-term effects of specific pollutants or combined exposures.