Related Experiment Videos
Elongation of growth cone filopodia observed with video-enhanced differential interference contrast microscopy
H Tatsumi1, H Sasaki, Y Katayama
1Department of Autonomic Physiology, Tokyo Medical and Dental University, Japan.
The Japanese Journal of Physiology
|January 1, 1993
Abstract:
Dynamics of filopodia configuration from growth cones of neurons isolated from the rat central nervous system were analyzed by using video-enhanced differential interference contrast microscopy. Rapid elongation of filopodia from growth cones and dendrites was observed when high K+ Krebs solution was applied to the growth cones. The maximum speed of the elongation was about 1 micron/s. The filopodia suspended in control Krebs solution moved at random. Retraction of the filopodia was observed within a few minutes after high K+ stimulation.