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Experimental seizure-induced brain damage: electrophysiological, metabolic and pathological correlation
T Tanaka1, T Fujita, K Yamamoto
1Department of Neurosurgery, Asahikawa Medical College, Japan.
The Japanese Journal of Psychiatry and Neurology
|June 1, 1993
Abstract:
Limbic seizures elicited by an intra-amygdaloid KA injection is the only and unique model which can produce unilateral hippocampal degenerative lesions and atrophy. This model is important not only to investigate neurophysiological epileptogenesis but also to study the causative process of human mesial temporal sclerosis observed in patients with intractable complex partial seizure.