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Stroke mortality in Spain, 1901-1986

M J Barrado-Lanzarote1, J de Pedro-Cuesta, J Almazan-Isla

  • 1Department of Applied Epidemiology, National Centre for Epidemiology, Institute of Health Carlos III, Madrid, Spain.

Neuroepidemiology
|January 1, 1993
PubMed
Summary

Stroke mortality in Spain significantly decreased by two-thirds between 1901 and 1986. This decline, particularly for hemorrhagic and ischemic stroke, occurred before widespread use of antihypertensive drugs.

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Area of Science:

  • Epidemiology
  • Public Health
  • Neurology

Background:

  • Stroke remains a significant cause of mortality globally.
  • Understanding long-term trends in stroke mortality is crucial for public health planning.
  • Spain provides a unique demographic and healthcare context for studying mortality patterns.

Purpose of the Study:

  • To analyze trends in stroke mortality in Spain from 1901 to 1986.
  • To compare Spain's stroke mortality rates with other European countries.
  • To investigate the timing of mortality declines in relation to medical interventions.

Main Methods:

  • Analysis of age-adjusted mortality data for stroke as the underlying cause of death.
  • Calculation of Standardized Mortality Ratios (SMR) from 1901 to 1986.
  • Comparison of mortality trends for hemorrhagic and ischemic stroke subtypes.

Main Results:

  • Overall stroke mortality in Spain decreased by approximately two-thirds during the study period.
  • Age-adjusted mortality rates in 1986 were 114.4/100,000 for males and 100.6/100,000 for females.
  • Significant declines were observed for hemorrhagic stroke since 1950 and ischemic stroke since 1973.
  • Mortality rates plateaued between 1950-1970 and potentially again in the early 1980s.
  • The recent drop in stroke mortality preceded the widespread use of antihypertensive drugs.

Conclusions:

  • Stroke mortality in Spain is at a medium level compared to other European nations.
  • The observed mortality patterns align with those reported for other industrial countries.
  • The decline in stroke mortality suggests factors beyond antihypertensive drug use may be significant.

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