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Bacterial plaque and enamel caries

¹College of Stomatology, West China University of Medical Sciences, Chengdu.

Chinese Medical Sciences Journal = Chung-Kuo I Hsueh K'O Hsueh Tsa Chih

|March 1, 1993

Summary

Bacterial plaque directly correlates with enamel caries development. The liquid phase of plaque is most active in causing tooth decay, challenging previous theories and confirming plaque

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Area of Science:

Oral microbiology
Dental caries research

Background:

Bacterial plaque is a known factor in dental caries.
Previous theories on enamel demineralization require further investigation.

Purpose of the Study:

To investigate the relationship between bacterial plaque and enamel caries.
To identify the active components and mechanisms of plaque in caries formation.

Main Methods:

Topographic examination of plaque and enamel caries distribution.
In vitro caries-like lesion production using human plaque samples.
Analysis of plaque phases and proteolytic activity.
Development of an in vitro multibacterial artificial plaque model.

Main Results:

A strong correlation was observed between plaque distribution and initial enamel caries.
Plaques from various patient groups induced caries-like lesions in vitro, with periodontal plaque causing shallower lesions.
The liquid phase of plaque was identified as the primary cariogenic agent.
No proteolytic activity of plaque fluid on enamel proteins was detected, refuting Gottleib's proteolysis theory for enamel caries.
The artificial plaque model closely mimicked natural plaque structure and induced caries-like lesions.

Conclusions:

Bacterial plaque plays a significant role in enamel caries development.
The liquid phase of plaque is the key cariogenic component.
The findings do not support the proteolysis theory of enamel caries and highlight the importance of plaque composition and activity.

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