Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cephalic phase insulin release in bulimia

A Moyer1, J Rodin, N Cummings

  • 1Department of Psychology, Yale University, New Haven, CT.

The International Journal of Eating Disorders
|November 1, 1993
PubMed
Summary

Bulimics show normal cephalic phase insulin release (CPIR) profiles, suggesting binge eating is not solely driven by physiological responses to food cues. Mood, not CPIR, correlated with binge desire in bulimics.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corrigendum to "Healthcare-worker-associated outbreak of Panton-Valentine-leukocidin-producing meticillin-sensitive Staphylococcus aureus in a large neonatal unit in London: successful targeted suppression therapy following failure of mass suppression therapy" [J Hosp Infect 122 (2022) 148-156].

The Journal of hospital infection·2025
Same author

Novel Measurement of the Neutron Magnetic Form Factor from A=3 Mirror Nuclei.

Physical review letters·2024
Same author

Revealing the short-range structure of the mirror nuclei <sup>3</sup>H and <sup>3</sup>He.

Nature·2022
Same author

Computational design of mechanically coupled axle-rotor protein assemblies.

Science (New York, N.Y.)·2022
Same author

Healthcare-worker-associated outbreak of Panton-Valentine-leukocidin-producing meticillin-sensitive Staphylococcus aureus in a large neonatal unit in London: successful targeted suppression therapy following failure of mass suppression therapy.

The Journal of hospital infection·2022
Same author

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.

Blood·2020

Area of Science:

  • Endocrinology
  • Neuroscience
  • Eating Disorders

Background:

  • Cephalic phase secretions, including cephalic phase insulin release (CPIR), are triggered by food cues and may influence metabolism and eating behavior.
  • Altered CPIR is hypothesized to contribute to binge eating in individuals with bulimia nervosa, who often exhibit endocrine abnormalities.

Purpose of the Study:

  • To investigate differences in CPIR profiles between individuals with bulimia nervosa and controls.
  • To examine the effect of food ingestion on subsequent CPIR.
  • To explore the relationship between mood, desire to binge, and CPIR in bulimia nervosa.

Main Methods:

  • Comparison of CPIR magnitude and profile in bulimics versus controls.
  • Assessment of CPIR changes following food ingestion.
  • Correlation analysis of mood, desire to binge, and CPIR.

Main Results:

  • Bulimics exhibited no significant abnormalities in their CPIR profile compared to controls.
  • Biological variables, including CPIR, were not associated with hunger or desire to binge.
  • Dysphoric moods were significantly related to the desire to binge in individuals with bulimia nervosa.

Conclusions:

  • The findings suggest that CPIR is not a primary physiological driver of binge eating in bulimia nervosa.
  • Mood state appears to be a more significant factor than physiological responses in precipitating binge episodes.
  • Binge eating in bulimia nervosa likely involves complex interactions between psychological and physiological factors, rather than solely altered CPIR.

Related Experiment Videos