A complex mutable polymorphism located within the fragile X gene

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Updated: Nov 8, 2026

A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene
08:22

A Robust Polymerase Chain Reaction-based Assay for Quantifying Cytosine-guanine-guanine Trinucleotide Repeats in Fragile X Mental Retardation-1 Gene

Published on: September 16, 2019

N Zhong1, C Dobkin, W T Brown

  • 1Department of Human Genetics, New York State Institute for Basic Research in Developmental Disabilities, Staten Island 10314.

Nature Genetics
|November 1, 1993
PubMed

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X-inactivation01:58

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The human X chromosome contains over ten times the number of genes as in the Y chromosome. Since males have only one X chromosome, and females have two, one might expect females to produce twice as many of the proteins, with undesirable results.