[Experimental study on the interaction of fibronectin with oral Streptococci]

Interaction of fibronectin (Fn) with Streptococcus mutans, S. sorbrinus, and S. milleri is demonstrated by an enzyme-linked immunosorbent assay (ELISA). The results show that the three strains are able to adhere to Fn. The interaction may be strengthened while the concentration of Fn increases (q test P < 0.01). The ability of adherence among S. mutans, S. sorbrinus and S. milleri is different in Fn high concentration (q test P < 0.01). It is speculated the free Fn in saliva may serve as an agglution for elimination of the organisms from the oral cavity, or as a receptor when immobilized on the tooth surface for cariogenic streptococci to form plaque. A balance between these two functions of Fn may play a role in modulating the microbial ecological environment of the oral cavity.