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[Ventricular late potentials in patients with diabetes mellitus]

N W Tong1, T G Yang, J Z Liang

  • 1Department of Medicine, First University Hospital, West China University of Medical Sciences, Chengdu.

Zhonghua Nei Ke Za Zhi
|July 1, 1993
PubMed

Insights

Ventricular late potentials (VLP) are more common in coronary heart disease (CHD) and diabetic patients than in healthy individuals. VLP measurement may detect subclinical diabetic cardiomyopathy and predict cardiac events.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Diabetology

Context:

  • Coronary heart disease (CHD) and diabetes mellitus are significant risk factors for cardiovascular complications.
  • Subclinical cardiac dysfunction in diabetic patients often goes undetected by standard electrocardiogram (ECG) and echocardiography (UCG).
  • Ventricular late potentials (VLP) are potential indicators of myocardial electrical instability.

Purpose:

  • To investigate the prevalence of VLP in diabetic patients without clinical cardiomyopathy compared to CHD patients and normal subjects.
  • To assess the utility of VLP as a marker for subclinical diabetic cardiomyopathy.
  • To explore the association between VLP and the risk of ventricular arrhythmia and sudden cardiac death in diabetic populations.

Summary:

  • A matched control study measured VLP in 31 normal subjects, 31 CHD patients, and 31 diabetic patients with normal ECG and UCG.
  • The positive VLP rate was significantly higher in the CHD group (45.16%) than in the diabetic group (19.35%) and normal subjects (0%).
  • Despite normal ECG and UCG, 19.35% of diabetic patients exhibited VLP, suggesting subclinical myocardial changes.

Impact:

  • VLP measurement may serve as a valuable tool for early detection of subclinical diabetic cardiomyopathy.
  • Identifying patients with VLP could aid in predicting the risk of ventricular arrhythmias and sudden cardiac death in diabetic individuals.
  • This technique offers a potential non-invasive method to stratify cardiac risk in diabetic patients beyond conventional assessments.

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