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Updated: Sep 23, 2026

Pharmacologic Induction of Epidermal Melanin and Protection Against Sunburn in a Humanized Mouse Model
Published on: September 7, 2013
Melanoma in prepubertal children
J M Pensler1, J Hijjawi, A S Paller
1Divisions of Plastic Surgery, Children's Memorial Hospital, Chicago, IL.
Abstract:
Malignant melanoma in prepubertal children is a rare event. Nine patients, 9.0 +/- 2.4 years (mean +/- S.D.), presented with malignant melanoma between December, 1975 and August, 1991. The thickness of the lesions ranged from 0.57 to > 4 mm. All patients (n = 6) with stage I or II disease are presently alive. Prepubertal patients with malignant melanoma tend to exhibit thick lesions when initially diagnosed. Their survival appears to be comparable or increased relative to their adult counterparts.
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