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Related Experiment Videos

[Myokymia]

M Kaji1, H Shoji

  • 1First Department (Neurology) of Internal Medicine, Kurume University School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

Myokymia, an involuntary muscle spasm, presents with varied symptoms and is linked to several neurological conditions. Further research is needed to understand its underlying causes and mechanisms.

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Area of Science:

  • Neurology
  • Symptomatology

Context:

  • Myokymia involves involuntary, undulating muscle spasms, often accompanied by pain, itching, or dysautonomia.
  • It is frequently associated with underlying conditions like multiple sclerosis, hypothyroidism, and Guillain-Barré syndrome.
  • Normal neurological findings in myokymia cases are uncommon.

Purpose:

  • To define myokymia and its clinical characteristics.
  • To outline the diverse etiologies and classifications of myokymia.
  • To highlight the current gaps in understanding its pathogenesis.

Summary:

  • Myokymia is characterized by wave-like muscle contractions, resembling a 'worm's crawl'.
  • Classified as limb or facial myokymia, it can also present with hyperhidrosis (Issacs syndrome).

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  • The exact pathogenesis at the neuromuscular junction, peripheral nerve, or spinal cord remains undetermined, despite various proposed theories.

    • Impact:

    • Enhances understanding of a rare movement disorder.
    • Provides a basis for further etiological and pathogenetic research.
    • Aids in differential diagnosis by associating myokymia with specific diseases.