Introduction and history of the use of electroencephalography in animal drug studies

A brief review of the development and the state-of-the-art of EEG methods used to study drug effects is presented. Classification systems based on drug effects in animals kept awake artificially, and based on drug effects on the sleep-wake state duration and distribution are discussed. It is concluded that the techniques are there and the time is ripe to develop animal EEG-based drug classification systems with high predictive ability.