Recurrence of nanophthalmic uveal effusion

A patient with nanophthalmic uveal effusion had a recurrence 7 months after the initial sclerectomies and sclerostomies. The effusion was cured by repeating the procedure. Specimens obtained at the first operation showed interlacing collagen lamellae and thin collagen bundles with an electron-dense deposit in the perifibrillar space. Specimens from the second operation showed disarranged collagen bundles with closely packed thin collagen fibrils. Collagen lamellae were not found. The regenerated scleral tissue was thought to interfere with the transscleral outflow and to block the bypass route, thus resulting in the recurrence of uveal effusion.