Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Hematologic changes in patients chronically exposed to benzene]

M A Ruiz1, J Vassallo, C A de Souza

  • 1Setor de Hematologia, Faculdade de Ciências Médicas de Santos (FCMS), SP, Brasil.

Revista De Saude Publica
|April 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Distinct proteomic profiles of plasma-derived extracellular vesicles in healthy, benign, and triple-negative breast cancer: candidate biomarkers for liquid biopsy.

Scientific reports·2025
Same author

A quantitative evaluation of aerosol generation during cardiopulmonary resuscitation.

Anaesthesia·2023
Same author

War and disaster are forcing a major rethink around mass casualty management.

BMJ military health·2023
Same author

Thyroid dysfunction in pregnancy - a retrospective observational analysis of a Maltese cohort.

BMC pregnancy and childbirth·2022
Same author

[A comparative study of recreational screen time in neurodevelopmental disorders].

Revista de neurologia·2022
Same author

[Sleep and academic performance in university students: a systematic review].

Revista de neurologia·2020

Chronic benzene exposure causes early hematological changes like macrocytosis and lymphopenia. Bone marrow abnormalities, including hypocellularity and mastocytosis, are also observed, highlighting a significant public health concern.

Area of Science:

  • Hematology
  • Toxicology
  • Public Health

Context:

  • Investigates hematological and bone marrow abnormalities in patients with chronic benzene exposure.
  • Examines metabolic biotransformation and toxicity mechanisms of benzene.
  • Highlights the public health implications of benzene toxicity.

Purpose:

  • To describe and discuss hematological data in benzene-exposed patients.
  • To identify early hematological signs of benzene toxicity.
  • To demonstrate bone marrow abnormalities using cytological and histological methods.

Summary:

  • Macrocytosis and lymphopenia are identified as the earliest indicators of benzene toxicity.
  • Bone marrow examination reveals global hypocellularity, primarily affecting the granulocytic series.

Related Experiment Videos

  • Additional abnormalities include mastocytosis, eosinophilia, megakaryocytic changes, inflammation, and dysmyelopoiesis.

    • Impact:

    • Emphasizes the significance of peripheral blood abnormalities in benzene exposure.
    • Underscores the need for a critical approach to managing benzene toxicity as a public health issue.
    • Provides comprehensive data on hematological and bone marrow effects for further research and clinical guidance.