Clinical and pathological investigation of endometrial mixed mesodermal tumor

Four cases of mixed mesodermal tumor (MMT) of uterine origin were histologically and cytologically studied. In the case of occurrence of rhabdomyosarcoma, the cells in the aspiration smear appeared independently and sporadically and were relatively large in size and polyhedral in shape. The cell margins were not clearly distinguishable, and the cytoplasm was non-uniformly and heavily stained light green in general except for some pale red eosinophilic areas. The swollen and elliptical nuclei had a high N/C ratio. The chromatin showed a densely stained coarse granular pattern, and the nuclear margin was expanded. On the imprint smear, the cells contained abundant cytoplasm with amoeboid protrusions. The cytoplasm was light green in general, was filled with granules of various sizes which were non-uniformly and heavily stained. The chromatin showed coarse granulation, and a large nucleolus was observed.