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[Hemodynamic variable analysis in patients with systemic arterial hypertension undergoing physical exercise]

S F de Oliveira1, J A Ramires, M C Solimene

  • 1Instituto do Coração do Hospital das Clínicas, FMUSP.

Arquivos Brasileiros De Cardiologia
|June 1, 1993
PubMed
Summary

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Moderate hypertensive patients show distinct hemodynamic responses to exercise. Group I relies on inotropism, while Group II adjusts by decreasing afterload, indicating potential vasomotor tone changes.

Area of Science:

  • Cardiovascular Physiology
  • Exercise Physiology

Background:

  • Understanding exercise-induced hemodynamic changes is crucial for managing hypertension.
  • Moderate hypertensive patients exhibit varied responses to physical exertion.

Purpose of the Study:

  • To investigate exercise-induced hemodynamic alterations in moderate hypertensive patients.
  • To differentiate cardiac function and circulatory adjustments during exercise.

Main Methods:

  • Twenty-nine hypertensive patients underwent supine cycloergometer exercise (50W and 100W) during cardiac catheterization.
  • Hemodynamic variables including cardiac index (CI), stroke volume (SV), and vascular resistance were measured.
  • Patients were categorized into two groups based on cardiac index (GI: >2.5 ml/min/m², GII: <2.5 ml/min/m²).

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Main Results:

  • While mean arterial pressure (MAP), heart rate (HR), and pressures were similar, stroke volume (SV), pulmonary arterial resistance (PAR), and systemic arterial resistance (SAR) differed between groups during exercise.
  • Group I showed stable pulmonary arterial resistance (PAR) and increased MAP, PAR, SV, and SAR with exercise.
  • Group II demonstrated increased HR, PAR, and SAR with exercise.

Conclusions:

  • Cardiac function in Group I appears primarily dependent on inotropism.
  • In Group II, cardiac function seems to rely on afterload reduction (PAR and SAR), suggesting functional changes in vasomotor tone.
  • These adaptive mechanisms can manifest even at higher exercise intensities (100W).