[Hyperkinetic syndromes associated with hypothiaminemia and corrected by administration of vitamin B 1]

High-output states combining tachycardia, increased cardiac output and raised blood pressure are often seen in clinical practice with causes other than the classical ones (hyperthyroidism anaemia and arterio-venous fistulae). Noticing how these syndromes ressemble cardiac beri-beri, the authors looked for hypothiaminaemia in these patients. On the 25 cases studied, two were particularly interesting as there was frank hypothiaminaemia, and also as treatment with vitamin B1 corrected not only the biochemical disorder but also the clinical symptoms, and led to lessening of the trachyardia and a reduction in cardiac output and blood pressure.