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N E. coli, inducible DNA repair is error-prone with regard to lethality
1Department of Radiation Oncology & Nuclear Medicine, Hahnemann University, Philadelphia, Pennsylvania 19102.
Biochemical and Biophysical Research Communications
|December 30, 1993
Abstract:
The umuC gene is a member of the inducible SOS repair network in E. coli. The experiments reported here indicate that the product of the umuC locus can make lethal mistakes during its normal repair function. Such "lethal repair" may be a major factor in establishing a cell's sensitivity to radiation.