Local treatment of thrombophlebitis with essaven gel

Essaven Gel contains aescin, heparin and essential phospholipids (EPL). It was administered locally in 15 patients suffering from thrombotic inflammation of tibial superficial veins. The effect of Essaven Gel on prostaglandin synthetase activity was also studied. In 12 patients a positive result was obtained in the form of anti-inflammatory action, diminution of pain, edema, excessive warmth and flushing. The anti-inflammatory action proceeds without any participation of prostaglandin synthetase.