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Recurrent t(12;19)(q13;q13.3) in intracranial and extracranial hemangiopericytoma
1Institute of Human Genetics, University of the Saar, Homburg/Saar, Germany.
Cancer Genetics and Cytogenetics
|December 1, 1993
Abstract:
We report on a recurrent intracranial hemangiopericytoma cytogenetically studied after short-term culture. The tumor had a uniform karyotype 47,XX,add(7)(q21),t(12;19)(q13;q13.3),del(13)(q14q22), +21. Remarkably, one case with an identical reciprocal (12;19) translocation has been previously reported as the sole cytogenetic change in a recurrent retroperitoneal hemangiopericytoma. This nonrandom structural change may characterize a subentity of hemangiopericytoma and might be of diagnostic value.