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Teratomas in pediatric age group: experience with 75 cases
A K Sharma1, C S Sharma, A K Gupta
1Department of Pediatric Surgery, S.M.S. Medical College, Jaipur.
Indian Pediatrics
|May 1, 1993
Summary
Pediatric teratomas, especially sacrococcygeal, require early recognition and complete surgical excision for optimal outcomes. Early presentation and mature histology significantly improve survival rates in children under 12.
Area of Science:
- Pediatric Oncology
- Surgical Pathology
- Developmental Biology
Background:
- Teratomas are congenital tumors with diverse histology and locations.
- In pediatric patients, early diagnosis and treatment are crucial for prognosis.
Purpose of the Study:
- To review clinicopathological features of pediatric teratomas.
- To identify prognostic factors influencing outcomes in young patients.
Main Methods:
- Retrospective review of 75 pediatric teratoma cases under 12 years.
- Analysis of tumor site, histology, treatment, and survival data.
Main Results:
- Most common site: sacrococcygeum (49/75); 74% presented within the first year of life.
- Complete excision yielded 95% survival for mature teratomas; immature/malignant types required multimodal therapy.
- Age at presentation and histology impacted prognosis, particularly for sacrococcygeal teratomas.
Conclusions:
- Early recognition and complete surgical excision are vital for pediatric teratomas.
- Histology and age at presentation are key prognostic indicators.
- Multimodal therapy improves outcomes for immature and malignant teratomas.