Related Experiment Videos
Mediastinal Castleman disease: CT findings
1Department of Radiology, College of Medicine, Seoul National University, Republic of Korea.
Journal of Computer Assisted Tomography
|January 1, 1994
Summary
Computed tomography (CT) imaging can help diagnose mediastinal Castleman disease. This study characterized CT findings for hyaline-vascular and plasma cell types of this rare lymphoproliferative disorder.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Castleman disease is a rare lymphoproliferative disorder.
- Mediastinal involvement is less common but significant.
Purpose of the Study:
- To characterize computed tomography (CT) findings in mediastinal Castleman disease.
- To correlate CT features with Castleman disease subtypes.
Main Methods:
- Retrospective review of CT scans from 10 patients with mediastinal Castleman disease.
- Analysis of lesion size, location, enhancement patterns, and calcifications.
Main Results:
- Hyaline-vascular type: well-demarcated, round masses (2-7 cm) with homogeneous enhancement, often in the hilum.
- Calcifications were noted centrally in one hyaline-vascular case.
- Plasma cell type: multiple small, homogeneously enhancing mediastinal and supraclavicular nodes.
Conclusions:
- CT findings can suggest preoperative diagnosis of mediastinal Castleman disease.
- Distinct CT features may help differentiate subtypes.