[Middle weight molecules before and after detoxification in patients with peritonitis]

The dynamics of changes of the middle mass molecule (MMM) content in blood serum and peritoneal exudate was studied in 193 patients before and after different methods of detoxification: intraoperative cleansing of the abdominal cavity in closed treatment, planned stage cleansing in open treatment of peritonitis, hemosorption, therapeutic plasmapheresis, sorption through a pig spleen. The control group was made up of 88 donors and 16 patients with an urgent abdominal disease without signs of peritonitis. The diagnostic value of MMM and the expediency of combining surgical methods for cleansing of the abdominal cavity with methods of extracorporeal detoxification are shown.