Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diabetic nephropathy: evaluation with renal duplex Doppler US

J F Platt1, J M Rubin, J H Ellis

  • 1Department of Radiology, University of Michigan Hospitals, Ann Arbor 48109-0030.

Radiology
|February 1, 1994
PubMed
Summary

Doppler ultrasonography (US) shows elevated resistive index (RI) in established diabetic nephropathy but is often normal in early stages. Renal Doppler US accurately indicates renal function but offers no significant advantage over conventional tests for diabetic kidney disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mass-like peripheral zone enhancement on CT is predictive of higher-grade (Gleason 4 + 3 and higher) prostate cancer.

Abdominal imaging·2014
Same author

Renal remodeling in the first 24 months after abdominal radiotherapy.

Practical radiation oncology·2014
Same author

[Provisional pacemaker implantation guided by pocket echocardiography].

Medicina intensiva·2012
Same author

Unknown ESUR cases 2004.

Abdominal imaging·2006
Same author

3-D correlation-based speckle tracking.

Ultrasonic imaging·2005
Same author

Standardization of power Doppler quantification of blood flow in the human fetus using the aorta and inferior vena cava.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2005

Area of Science:

  • Nephrology
  • Radiology
  • Diabetology

Background:

  • Diabetic kidney disease (DKD) is a major complication of diabetes mellitus.
  • Early detection and monitoring of DKD are crucial for patient outcomes.
  • Conventional methods for evaluating DKD include clinical and laboratory tests.

Purpose of the Study:

  • To compare the efficacy of Doppler ultrasonography (US) with conventional clinical and laboratory tests in evaluating diabetic renal disease.
  • To assess the utility of renal resistive index (RI) measurement in diagnosing and monitoring DKD.

Main Methods:

  • Ninety-eight patients with diabetes mellitus underwent renal Doppler US for resistive index (RI) measurement.
  • US data were compared with clinical variables and follow-up data.

Related Experiment Videos

  • Patients were categorized into groups: no nephropathy, early nephropathy, and established nephropathy.

    • Main Results:

    • Mean RI was not significantly different between patients without nephropathy (0.62 ± 0.09) and those with early nephropathy (0.64 ± 0.09).
    • Patients with established nephropathy had a significantly higher mean RI (0.83 ± 0.11, P < .001).
    • Renal RI correlated strongly with serum creatinine (r = .64) and creatinine clearance (r = .80). An elevated RI (≥ 0.70) indicated impaired renal function and poor outcomes. Absent diastole (RI = 1.0) was an ominous sign, with 7% of patients requiring dialysis or transplantation.

    Conclusions:

    • Resistive index (RI) is typically elevated in established diabetic nephropathy but often normal in early clinical stages.
    • Renal Doppler US provides an accurate assessment of renal function in DKD.
    • Doppler US does not offer a significant advantage over conventional tests for evaluating diabetic renal disease.