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Renal artery blood flow: quantitation with phase-contrast MR imaging with and without breath holding
J F Debatin1, R H Ting, H Wegmüller
1Department of Radiology, Stanford University School of Medicine, Calif.
Purpose:
To compare the accuracy of 16-frame cine phase-contrast (PC) magnetic resonance (MR) imaging with those of two breath-hold PC techniques in the measurement of renal artery blood flow.
Materials And Methods:
In vitro flow measurements were performed in a segment of harvested human artery embedded in gel. For the cine PC acquisition, respiratory motion was simulated. In eight subjects with recently obtained para-amino-hippurate-clearance renal blood flow data, renal artery flow measurements were subsequently performed with two breath-hold imaging techniques and with cine PC imaging during shallow respiration.
Results:
Breath-hold sequences were significantly more accurate than conventional cine PC sequences both in vitro (P < .005) and in vivo (P < .05). Cine PC imaging tended to overestimate flow (in vivo mean, 24.47% +/- 9.94), reflecting artifactual enlargement of the apparent vessel size.
Conclusion:
Reliable blood flow measurements in the renal artery are possible with breath-hold PC MR imaging.