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Related Experiment Videos

Abdominal MR imaging: evaluation of a fast spin-echo sequence

E K Outwater1, D G Mitchell, S Vinitski

  • 1Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107.

Radiology
|February 1, 1994
PubMed
Summary

Fast spin-echo (FSE) magnetic resonance (MR) imaging shows subtle differences in abdominal tissue contrast compared to conventional spin-echo (SE) sequences. These differences were significant for malignant liver lesions, improving their detection on FSE images.

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Area of Science:

  • Radiology
  • Medical Imaging
  • Magnetic Resonance Imaging

Background:

  • Conventional spin-echo (SE) T2-weighted sequences are standard for abdominal MR imaging.
  • Fast spin-echo (FSE) sequences offer faster acquisition times but may alter image contrast.
  • Understanding contrast differences is crucial for accurate diagnosis in liver disease.

Purpose of the Study:

  • To compare the contrast characteristics of abdominal tissues on T2-weighted magnetic resonance (MR) images acquired using conventional spin-echo (SE) and fast spin-echo (FSE) sequences.
  • To evaluate the diagnostic utility of FSE sequences for detecting malignant liver lesions.

Main Methods:

  • Forty-eight patients with known or suspected liver disease underwent 1.5 T MR imaging with both FSE and SE sequences.

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  • Signal intensity (SI), signal-to-noise (S/N), signal difference-to-noise (SD/N), and SI ratios were calculated for various abdominal tissues and liver lesions.
  • Statistical analysis compared the quantitative parameters between FSE and SE images.

    • Main Results:

    • FSE sequences demonstrated significantly lower signal difference-to-noise (SD/N) for most tissues compared to SE, except for fat.
    • Malignant liver lesions exhibited lower signal intensity ratios on FSE images versus SE images.
    • FSE images revealed significant differences in contrast between malignant liver lesions and benign lesions (hemangiomas or cysts), unlike SE images.

    Conclusions:

    • T2-weighted FSE sequences yield small but significant differences in abdominal tissue-to-liver contrast compared to conventional SE sequences.
    • These contrast alterations on FSE images may enhance the differentiation of malignant liver lesions from other pathologies.
    • FSE sequences represent a valuable alternative for abdominal MR imaging, particularly in the evaluation of liver disease.