Related Experiment Video
Updated: Aug 9, 2026

09:02
Validation of a Mouse Model to Disrupt LINC Complexes in a Cell-specific Manner
Published on: December 10, 2015
Congenital Horner's syndrome does not alter Lisch nodule formation
J S Mindel1, A E Rubenstein, S Wallace
1Department of Ophthalmology, Mount Sinai Medical Center, New York, NY.
Annals of Neurology
|January 1, 1994
Abstract:
A 21-year-old woman with neurofibromatosis type 1 (NF-1) had a unilateral congenital Horner's syndrome with resultant hypopigmentation of the affected iris. Lisch nodules, which are melanocytic hamartomas, were similar in number, size, and pigmentation in both eyes. The present findings suggest that the formation of Lisch nodules is not influenced by the presence or absence of sympathetic innervation of the iris.

