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Related Experiment Videos

Cancer pain management

J E Charlton1

  • 1Pain Management Unit, Royal Victoria Infirmary, Newcastle upon Tyne, Great Britain.

Cahiers D'Anesthesiologie
|January 1, 1993
PubMed
Summary
This summary is machine-generated.

Most cancer pain is manageable with oral medications, but 10-20% of patients experience opioid resistance. Effective pain management involves strong opioids and adjunctive therapies for challenging cases.

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Area of Science:

  • Oncology
  • Pain Management
  • Pharmacology

Background:

  • Most cancer pain is manageable with oral analgesics.
  • However, 10-20% of patients exhibit opioid resistance, necessitating alternative strategies.
  • Mild pain is treated with paracetamol and NSAIDs, while strong opioids are often required for severe pain.

Purpose of the Study:

  • To review current approaches for managing cancer pain, particularly in opioid-resistant cases.
  • To discuss the role of strong opioids and adjunctive therapies.
  • To explore alternative pain relief methods beyond conventional analgesics.

Main Methods:

  • Literature review of cancer pain management strategies.
  • Discussion of pharmacological interventions, including strong opioids and combination therapies.

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  • Exploration of interventional pain management techniques.

    • Main Results:

    • Strong opioids are frequently necessary for cancer pain, despite potential side effects.
    • Adjunctive therapies like steroids and antidepressants can enhance pain relief.
    • Interventional procedures such as nerve blocks and acupuncture offer additional options for refractory pain.

    Conclusions:

    • Opioid-resistant cancer pain requires a multimodal approach.
    • Combining strong opioids with other medications and interventions is crucial for effective management.
    • Non-pharmacological methods can play a supportive role in alleviating cancer pain.