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Systemic diseases associated with intermediate uveitis

S A Boskovich1, C Y Lowder, D M Meisler

  • 1Department of Ophthalmology, Cleveland Clinic Foundation, OH 44195.

Cleveland Clinic Journal of Medicine
|November 1, 1993
PubMed
Summary
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Intermediate uveitis, an eye inflammation, is often linked to systemic diseases like sarcoidosis and multiple sclerosis. Regular medical evaluations are crucial for patients diagnosed with this condition.

Area of Science:

  • Ophthalmology
  • Immunology
  • Systemic Diseases

Background:

  • Intermediate uveitis involves inflammation of the vitreous, vitreous base, and peripheral anterior retina and choroid.
  • It can occur as an idiopathic condition or be associated with systemic disorders like multiple sclerosis and sarcoidosis.

Purpose of the Study:

  • To determine the clinical characteristics of intermediate uveitis.
  • To investigate the association between intermediate uveitis and systemic diseases.

Main Methods:

  • Retrospective analysis of 83 patients diagnosed with intermediate uveitis.
  • Data collected between 1970 and 1991.

Main Results:

  • Systemic disorders were identified in 31.3% of patients.

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  • Commonly associated systemic conditions included sarcoidosis (10 patients), multiple sclerosis (6 patients), and thyroid abnormalities (4 patients).
  • Ocular findings encompassed cystoid macular edema, perivascular retinal sheathing, cataracts, and optic disc edema.

    • Conclusions:

    • Intermediate uveitis frequently coexists with systemic diseases.
    • Patients require thorough systemic evaluation and consistent follow-up care.