Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Radiation synovectomy revisited

E Deutsch1, J W Brodack, K F Deutsch

  • 1Mallinckrodt Medical, Inc., St. Louis, MO 63134.

European Journal of Nuclear Medicine
|November 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.

Annals of oncology : official journal of the European Society for Medical Oncology·2015
Same author

Implementation of the global risk analysis in pulsed-dose rate brachytherapy: methods and results.

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2015
Same author

Focal or combined modality for the management of brain metastasis: did high tech radiotherapy superseded drug-radiotherapy combination?

Annals of oncology : official journal of the European Society for Medical Oncology·2014
Same author

Radiosensitization by a novel Bcl-2 and Bcl-XL inhibitor S44563 in small-cell lung cancer.

Cell death & disease·2014
Same author

[Stereotactic body radiation therapy in the management of liver tumours].

Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique·2014
Same author

The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy.

The British journal of radiology·2014

Radiation synovectomy effectively treats rheumatoid arthritis symptoms. New methods aim to reduce radioactivity leakage, enhancing this nuclear medicine therapy for wider use.

Area of Science:

  • Nuclear Medicine
  • Rheumatology

Background:

  • Rheumatoid arthritis (RA) management often involves invasive procedures.
  • Radiation synovectomy offers a less invasive nuclear medicine approach for RA.
  • Historical data on radiation synovectomy efficacy exists but lacks extensive controlled trials.

Purpose of the Study:

  • To review and summarize clinical outcomes of radiation synovectomy for rheumatoid arthritis from 1950-1992.
  • To assess the efficacy of radiation synovectomy in controlling RA symptoms.
  • To identify limitations and future directions for radiation synovectomy.

Main Methods:

  • Review of clinical results from radiation synovectomy procedures.
  • Analysis of data from 1950s through 1992.
  • Consideration of limitations due to trial quality and follow-up.

Related Experiment Videos

Main Results:

  • Radiation synovectomy demonstrates clear efficacy in alleviating rheumatoid arthritis symptoms.
  • Despite efficacy, the procedure's adoption is limited by concerns over radioactive leakage.
  • Potential for off-target organ radiation exposure is a significant drawback.

Conclusions:

  • Radiation synovectomy is an effective nuclear medicine treatment for rheumatoid arthritis.
  • Minimizing radioactive leakage is crucial for broader clinical application.
  • Advancements in radiolabeled particle preparation may unlock the full potential of radiation synovectomy.