[Periodicity complexes in the EEG of necrotising herpes-encephalitis (author's transl)]

The clinical and electroencephalographic observations in two patients with verified necrotising herpes-encephalitis are presented. In one of the ill persons it was possible to isolate the virus. With these two observations four additional ones published previously are compaired electroencephalographically. Thereby the EEG reveal a certain variation in form and local distribution of periodic discharges (bursts) from relatively regularly recurring slow waves to stereotype periodicity complexes. Next an attempt is made to arrive at physiopathogenetic explanations for the EEG-changes by compairing the pathologico-anatomical findings of the six cases presented with those of ten more cases. The topographical distribution of the anatomical lesions in these inflammatory precesses seem to be of special importance for the occurence of the EEG-changes.