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[A case of Borrmann type 4 gastric cancer responding to sequential methotrexate and 5-fluorouracil combined with
T Nakagohri1, H Miyoshi, Y Tsunoda
1Second Dept. of Surgery, Chiba University, School of Medicine.
Abstract:
A case of Borrmann type 4 gastric cancer responding to sequential methotrexate and 5-fluorouracil combined with cis-diamminedichloroplatinum (CDDP) is reported. A 57-year-old woman was admitted to our hospital complaining of abdominal fullness. Upper gastrointestinal series and gastrofiberscopy revealed almost the entire stomach was involved with Borrmann type 4 cancer. Gastrectomy could not be performed because of peritoneal dissemination. However, the patient responded to sequential methotrexate and 5-fluorouracil therapy and CDDP administration. She enjoyed more than one year of hospital-free survival period and survived for almost two years.