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Updated: Aug 19, 2026

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children
Published on: December 31, 2017
Bacterial flora of the healthy skin in children
Insights
Antibiotic-resistant bacteria are common on children's skin, potentially spreading resistance to infections. Topical antiseptics are recommended over antibiotics for skin issues in children.
Area of Science:
- Microbiology
- Dermatology
- Pediatrics
Background:
- The skin's normal bacterial flora plays a crucial role in health and disease.
- Understanding the antibiotic resistance patterns of commensal skin bacteria is essential for effective treatment strategies.
Purpose of the Study:
- To investigate the bacterial spectrum and antibiotic resistance of the normal skin flora in healthy children.
- To assess the potential for antibiotic resistance transfer from commensal to pathogenic bacteria in pediatric skin infections.
Main Methods:
- Abrasion skin samples were collected from the upper back of 100 healthy children.
- Bacterial cultures were analyzed to determine the predominant species and their antibiotic resistance profiles.
Main Results:
- Staphylococcus albus was the most prevalent bacteria, followed by Sarcina and Corynebacteria.
- A significant proportion of the normal skin flora exhibited resistance to commonly used antibiotics.
Conclusions:
- The high prevalence of antibiotic-resistant strains in the normal skin flora raises concerns about resistance transfer to pathogens.
- Topical broad-spectrum antimicrobial agents (antiseptics) are recommended over systemic antibiotics for pediatric skin conditions due to widespread resistance.
Abstract:
The normal bacterial flora of the skin of 100 healthy children was studied in a paediatric practice with regard to the germ spectrum and the resistance constellation, by means of abrasion skin samples taken from the upper part of the back. Staphylococcus albus was by far the most predominant bacteria, followed by Sarcina bacteria and Corynebacteria. The high degree of pervasion of this physiological cutaneous flora with antibiotic-resistant strains increases the suspicion that in the case of florid bacterial skin infections in children, subsequent to traumatic or inflammatory changes of the integument, the antibiotic resistance of the normal resident flora can be transferred to the pathogenic flora. In view of the endemic resistance of pathogenic and saprobic strains of bacteria against practically all antibiotics at present used in paediatric practice, it is to be urgently recommended that instead of antibiotics topical braod-spectrum antimicrobial agents (antiseptics), e.g. clioquinol, triclosan, etc., should preferably be used.
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