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Updated: Jul 25, 2026

Assessing Therapeutic Angiogenesis in a Murine Model of Hindlimb Ischemia
Published on: June 8, 2019
[Short and long-term results of non-standard revascularization of the lower extremities]
Abstract:
A total of 125 patients with unreconstructable Stages III and IV lower extremity arterial occlusions were treated by an unconventional procedure (Ilizarov's procedure). The patients underwent longitudinal osteotomy, then distraction of the obtained bone break for 31-36 days, followed by its fixation for 45-60 days. Additionally, lumbar sympathectomy and arterial reconstruction were performed in 41 and 16 patients, respectively. During surgery bone fracture occurred in 2 cases. After intervention, local infectious complications were observed in 16 patients. A direct positive result was seen in 95 (76.0%) patients. In the long-term period (mean 21.6 months later), a positive result was seen in 83 (94.2%) of 88 examinees.
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