Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A frameless method for stereotactic radiotherapy

D Jones1, D A Christopherson, J T Washington

  • 1Northwest Medical Physics Center, Lynnwood, WA 98036-7306.

The British Journal of Radiology
|December 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combination of lovastatin, enalapril, and colchicine does not prevent restenosis after percutaneous transluminal coronary angioplasty.

The American journal of cardiology·1995
Same author

Caenorhabditis elegans UBC-1, a ubiquitin-conjugating enzyme homologous to yeast RAD6/UBC2, contains a novel carboxy-terminal extension that is conserved in nematodes.

DNA and cell biology·1995
Same author

Phase II trial of isotretinoin and recombinant interferon alfa-2a in metastatic colorectal carcinoma.

American journal of clinical oncology·1995
Same author

Characterization of a 17-kilodalton antigen of Bartonella henselae reactive with sera from patients with cat scratch disease.

Journal of clinical microbiology·1995
Same author

A portable regulatory element directs specific expression of the Caenorhabditis elegans ubiquitin gene ubq-2 in the somatic gonad.

Developmental biology·1995
Same author

Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression.

Molecular and cellular biology·1995

A frameless stereotactic multiple arc radiotherapy (SMART) method uses implanted cranial gold markers for precise tumor targeting. Screwing markers into the cranium improved stability, ensuring accurate radiotherapy delivery with sub-millimeter precision.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Neurosurgery

Background:

  • Stereotactic radiotherapy requires precise patient positioning.
  • Existing methods may involve invasive stereotactic frames.
  • Frameless techniques offer potential advantages in patient comfort and workflow.

Purpose of the Study:

  • To describe and evaluate a frameless method for stereotactic multiple arc radiotherapy (SMART).
  • To assess the precision and stability of a novel gold marker-based localization system.
  • To determine the clinical feasibility of the described technique.

Main Methods:

  • Implantation of three gold wire markers into the scalp.
  • Localization of markers and target using computed tomography or angiography.

Related Experiment Videos

  • Calculation of required couch movements using the ISOLOC computer program.
  • Refinement of positioning through repeated beam film analysis until sub-millimeter accuracy is achieved.
  • Modification to cranial screw fixation for improved marker stability.
  • Main Results:

    • The frameless SMART method allows for precise patient positioning.
    • Initial subcutaneous marker implantation showed instability in approximately 25% of patients.
    • Cranial screw fixation of markers significantly improved system stability.
    • Phantom studies and clinical treatments demonstrated sub-millimeter accuracy in target localization and delivery.

    Conclusions:

    • Frameless stereotactic multiple arc radiotherapy is feasible using cranial gold markers.
    • Cranial fixation of markers is crucial for achieving a stable reference system.
    • The described method offers a precise and potentially more comfortable alternative for radiotherapy delivery.