Related Experiment Video
Updated: May 28, 2026

En Face Detection of Nitric Oxide and Superoxide in Endothelial Layer of Intact Arteries
Published on: February 25, 2016
Endothelium-derived nitric oxide in the control of tissue perfusion and oxygen supply: physiological and
Abstract:
Since the development of specific NO-synthase inhibitors it has become possible to study the role of NO in the control of local blood flow and tissue oxygenation. Inhibition of NO-synthase induces hypertension and abnormal vasoconstriction, as well as tissue hypoxia and impaired adaptation of blood flow to increased tissue oxygen demands. These functional alterations are similar to those observed in a number of cardiovascular diseases. The present evidence that impaired endothelial function is a pathogenetic factor in the development of cardiovascular diseases is briefly reviewed.
More Related Videos
08:23Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
09:47Measurement of Endothelium-Dependent Vasorelaxation in the Mouse Thoracic Aorta Using Tensometric Small Volume Chamber Myography
Published on: August 12, 2022
Related Concept Videos
Regulation of Angiogenesis and Blood Supply
Nitric Oxide Signaling Pathway
Physiological Control of Respiration
Breathing, a seemingly passive process, is regulated by the respiratory center in the brainstem. This center coordinates the involuntary control of respirations, which means it occurs without conscious effort, ensuring a smooth and uninterrupted pattern.
Regulation of Ventilation
The body maintains ventilation by monitoring levels of carbon dioxide (CO2), oxygen (O2), and hydrogen ion concentration (pH) in the arterial blood. Among these factors, the level of CO2 plays a crucial...
Pathophysiology of Cardiac Performance
Structure of Blood Vessels
Autoregulation of Blood Flow
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.