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Cardiac involvement in systemic sclerosis

M S Chandalia1, C V Vanjani, A R Bhagwat

  • 1TN Medical College and BYL Nair Hospital, Bombay.

The Journal of the Association of Physicians of India
|October 1, 1993
PubMed
Summary
This summary is machine-generated.

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Systemic sclerosis patients often show cardiac issues. Cold stimulation revealed myocardial ischemia in only one of 17 patients, suggesting limited acute cardiac effects in this cohort.

Area of Science:

  • Cardiology
  • Rheumatology
  • Medical Imaging

Background:

  • Systemic sclerosis (SSc) is a multisystem autoimmune disease.
  • Cardiac involvement is a significant cause of morbidity and mortality in SSc.
  • Early detection of cardiac dysfunction is crucial for patient management.

Purpose of the Study:

  • To describe the clinical profile of systemic sclerosis patients.
  • To screen for cardiac involvement using various diagnostic tools.
  • To evaluate the effect of cold stimulation on myocardial function in SSc.

Main Methods:

  • 17 patients with systemic sclerosis were studied.
  • Standard investigations included ECG, echocardiography, and radionuclide ventriculography.
  • Computerized stress tests were performed before and after cold pressor testing.

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Main Results:

  • 10 patients had abnormal ECG findings.
  • 2 patients had mild pericardial effusion.
  • 5 patients had moderate pulmonary hypertension.
  • Echocardiography and radionuclide ventriculography showed no wall motion abnormalities.
  • One patient exhibited ischemia on stress testing after cold stimulation.

Conclusions:

  • Systemic sclerosis patients frequently present with ECG abnormalities, pericardial effusion, and pulmonary hypertension.
  • Standard echocardiography and radionuclide ventriculography may not detect acute myocardial dysfunction in SSc.
  • Cold stimulation revealed inducible ischemia in a small subset of SSc patients.