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Internal eye wall resection for posterior uveal melanoma
K J Lee1, G A Peyman, S Raichand
1Louisiana State University Medical Center School of Medicine, New Orleans.
Japanese Journal of Ophthalmology
|January 1, 1993
Summary
Internal surgical resection for posterior choroidal melanoma shows concerning long-term outcomes. Three of 23 patients died from metastatic choroidal melanoma, highlighting the aggressive nature of this eye cancer.
Area of Science:
- Ophthalmology
- Surgical Oncology
- Medical Oncology
Background:
- Posterior choroidal melanoma is a rare intraocular malignancy.
- Surgical resection is a treatment option for selected cases.
- Long-term outcomes data are crucial for treatment planning.
Purpose of the Study:
- To report the long-term follow-up results of internal surgical resection for posterior choroidal melanoma.
- To evaluate the visual acuity and survival rates after this surgical intervention.
Main Methods:
- Retrospective analysis of 23 patients who underwent internal surgical resection for posterior choroidal melanoma (1984-1991).
- Tumors located within 1-2 disc diameters of the optic disc or fovea.
- Follow-up ranged from 7 to 84 months.
Main Results:
- 43% of patients achieved visual acuity of 20/400 or better.
- Two patients required enucleation due to recurrence or complications.
- Three patients (13%) died from metastatic choroidal melanoma, with two having spindle B-cell tumors.
Conclusions:
- Internal surgical resection for posterior choroidal melanoma has significant risks, including metastasis and enucleation.
- Tumor histology (spindle B-cell) may be associated with poorer prognosis.
- Long-term surveillance is essential for patients treated with this approach.