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[Rapid cycling in bipolar disorders]
E A Knoppert-van der Klein1, C A Hoogduin, W A Nolen
1Psychiatrisch Ziekenhuis Endegeest, afd. Jelgersmapolikliniek, Oegstgeest.
Nederlands Tijdschrift Voor Geneeskunde
|January 15, 1994
Abstract:
Two patients, a woman aged 32 and a man aged 27 years, were suffering from rapid cycling bipolar disorder (i.e. a course with four or more episodes a year). Hypothyroidism and the use of antidepressants may be involved in the development of such a disease course. Treatment with carbamazepine was successful in both patients. Patients suffering from rapid cycling bipolar disorder should be treated with lithium or carbamazepine, or a combination of these. Antidepressants should only be used with great caution.