[Cellular reactions in contamination with various types of Mycobacterium in experimental study]

Characteristics of specific inflammation induced by intradental challenge with mycobacteria (MB) were studied cytologically and bacterioscopically. Mycobacterium tuberculosis hominis and bovis, BCG, atypical M. fortuitum in the 5th dilution by turbidity standard were administered into the root canals of a tooth and pulp cavities of 16 mongrel dogs (body mass 13-16 kg, age 1-4 years). Investigation of the dogs' organs and paradental tissues revealed that MB underwent L-transformation the speed of which depended on the species. Cellular reactions were also related to the agent species and form of vegetation. Cytobacterioscopic tests are proposed as additional diagnostic means and to validate therapeutic policy.