[Strategies in insulin treatment in insulin-dependent diabetes mellitus]

Late diabetic sequelae can be largely prevented by striving for near normoglycemic blood glucose control. In type-1 diabetes this can in most of the cases only be achieved by some sort of intensified insulin regimen. In this article the principle, advantages and drawbacks as well as the consequences for the patients' education are reviewed with respect to conventional, intensified 'conventional' and functional insulin treatment.