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An Alkali-burn Injury Model of Corneal Neovascularization in the Mouse
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Injury to the cornea due to fish bile

T Christoffersen1, E G Olsen

  • 1Department of Ophthalmology, University Hospital, Tromsł, Norway.

Scandinavian Journal of Work, Environment & Health
|October 1, 1993
PubMed
Summary

Fish bile caused chemical eye injuries in 14% of cases, primarily affecting fishermen. Prompt rinsing and medical care improved prognosis for these corneal erosions.

Area of Science:

  • Ophthalmology
  • Toxicology
  • Occupational Health

Background:

  • Chemical eye injuries pose a significant risk in certain occupations.
  • Understanding the specific agents causing ocular damage is crucial for prevention and treatment.

Observation:

  • A retrospective study analyzed 207 chemical eye injury cases in Northern Norway.
  • Fish bile was identified as the causative agent in 14% of these injuries.
  • The majority of affected individuals were professional fishermen or fish industry workers.

Findings:

  • Fish bile exposure resulted in superficial corneal erosions in 28 out of 29 documented cases.
  • Delayed medical attention in one instance led to severe corneal opacity.
  • Prompt and copious eye rinsing, coupled with adequate medical care, generally led to a favorable prognosis.

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Implications:

  • Fish bile is a notable occupational hazard for those in the fishing industry.
  • Immediate first aid, including thorough eye irrigation, is critical for mitigating fish bile-induced ocular damage.
  • Further research is needed to elucidate the specific mechanisms of corneal damage caused by fish bile.