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False DNA aneuploidy in canine and human neoplasms
A D Deitch1, R W de Vere White, B R Madewell
1Department of Urology, University of California, Davis 95817.
Anticancer Research
|November 1, 1993
Abstract:
In most cases, the appearance of aneuploid peaks in DNA histograms may be an artefact of tissue preparation or it may reflect non-stoichiometric dye binding of a cellular subpopulation rather than true DNA aneuploidy. This report reviews how false DNA aneuploidy can be recognized and eliminated from sample submitted for DNA flow cytometric analysis.