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Updated: Aug 14, 2026

Tissue Triage and Freezing for Models of Skeletal Muscle Disease
Published on: July 15, 2014
[Myopathies associated with tubular aggregates]
M S Carvalho1, E S Lusvarghi, A L Levy
1Clínica Neurológica (CN) da Faculdade de Medicina (FM), Universidade de São Paulo (USP), Brasil.
Abstract:
The authors report the case of a 58-year-old male patient with clinical and electromyographic features of myasthenia. Muscle biopsy with histochemistry and electronic microscopy made it possible to diagnose a myopathy associated with tubular aggregates. Attention is called to the fact that the anatomical pathologic alterations which were found may be present in a heterogenous group of patients showing a great variety of symptoms. Thus, there is no reason to consider the existence of a myopathy associated with tubular aggregates, since the anatomical and pathologic findings are inespecific and do not characterize any specific disease.
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