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Myasthenia gravis
1Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
Current Opinion in Immunology
|December 1, 1993
Abstract:
The cause of the myasthenics' pathogenic autoantibody response against the muscle acetylcholine receptor is an intriguing puzzle involving the thymus and its epithelial tumours, and possibly a variety of cross-reacting epitopes. Another fascinating challenge is to find ways of selectively inhibiting this response in the patients.