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Updated: Aug 9, 2026

Heterotopic Heart Transplantation in Mice
Published on: July 19, 2007
A suggested technique for "orthotopic" heart transplantation in a patient with situs inversus
D K Cooper1, Y Ye, J S Chaffin
1Oklahoma Transplantation Institute, Baptist Medical Center, Oklahoma City 73112.
Abstract:
We describe a technique for "orthotopic" heart transplantation in a patient with situs inversus. The left atrial, aortic, and pulmonary artery anastomoses were performed directly, in the usual manner. The recipient's right atrium was converted into a tunnel, and the donor's right atrium was left intact. Anastomoses were therefore required between the 2 inferior venae cavae (by direct end-to-end anastomosis) and the 2 superior venae cavae (necessitating the insertion of a Dacron-graft). We suggest that even simpler techniques, perhaps not requiring the use of an artificial vascular prosthesis, are possible.

