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Carotid body paraganglioma with coexistent pheochromocytoma in childhood
A S Varudkar1, H R Kokandkar, G G Gumaste
1Govt. Medical College, Aurangabad, Maharashtra, India.
Insights
A six-year-old boy with neck swelling and hypertension had surgery for carotid body paraganglioma and pheochromocytoma. Persistent hypertension was managed with medication, highlighting complex endocrine and vascular tumor management in pediatric cases.
Area of Science:
- Pediatric Endocrinology
- Vascular Surgery
- Oncology
Background:
- Carotid body paragangliomas and pheochromocytomas are rare neuroendocrine tumors.
- Coexistence of these tumors is exceptionally uncommon, particularly in pediatric patients.
- Hypertension is a common symptom associated with pheochromocytoma due to catecholamine excess.
Observation:
- A six-year-old male presented with a neck mass and significant hypertension.
- Diagnostic workup confirmed the presence of both carotid body paraganglioma and pheochromocytoma.
- Surgical excision of both tumors was performed.
Findings:
- Post-operative hypertension persisted despite the successful removal of both tumors.
- The persistent hypertension was effectively managed with antihypertensive pharmacotherapy.
- This case highlights the complex and potentially prolonged management of hypertension in pediatric patients with combined endocrine and vascular tumors.
Implications:
- This case underscores the importance of thorough pre-operative evaluation and post-operative monitoring for persistent or recurrent hypertension in pediatric patients with paraganglioma and pheochromocytoma.
- Management strategies may require a multidisciplinary approach involving pediatric endocrinologists, surgeons, and oncologists.
- Further research into the pathophysiology and long-term management of coexisting paraganglioma and pheochromocytoma in children is warranted.
Abstract:
A male child aged six years presented with a swelling in neck and hypertension. He was diagnosed to have and operated for Carotid body paraganglioma with Coexistent pheochromocytoma. Hypertension persisted even after excision of both the tumours which could be controlled with anti-hypertensive agents. The case is discussed with review of literature.