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The Mycobacterium bovis 32-kilodalton protein antigen induces human cytotoxic T-cell responses
1Department of Immunology, University of Ulm, Germany.
Infection and Immunity
|February 1, 1994
Abstract:
The 30-kDa protein (P32) is a mycobacterial secreted antigen which is homologous in Mycobacterium bovis and M. tuberculosis. In vitro, P32 induced T-cell proliferation. M. tuberculosis- or P32-stimulated T-cell lines lysed macrophages pulsed with P32 or M. tuberculosis, respectively. We conclude that P32 stimulates cytotoxic T cells specifically.