Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Do gonadal steroids regulate circadian rhythms in humans?

E Leibenluft1

  • 1Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, MD 20892.

Journal of Affective Disorders
|October 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential associations of conduct disorder, callous-unemotional traits and irritability with outcome expectations and values regarding the consequences of aggression.

Child and adolescent psychiatry and mental health·2022
Same author

Corrigendum to "Frontal alpha asymmetry moderates the relations between behavioral inhibition and social-effect ERN" [Biological Psychology (2019) 10-16].

Biological psychology·2021
Same author

Social anxiety and age are associated with neural response to social evaluation during adolescence.

Developmental cognitive neuroscience·2020
Same author

Early-childhood social reticence predicts SCR-BOLD coupling during fear extinction recall in preadolescent youth.

Developmental cognitive neuroscience·2019
Same author

Frontal alpha asymmetry moderates the relations between behavioral inhibition and social-effect ERN.

Biological psychology·2019
Same author

Investigating the genetic underpinnings of early-life irritability.

Translational psychiatry·2017

Gonadal steroids influence circadian rhythms. This study hypothesizes that estrogen shortens human circadian periods and improves sleep, with ongoing research to confirm these effects in women.

Area of Science:

  • Neuroendocrinology
  • Chronobiology
  • Reproductive Biology

Background:

  • Gonadal steroids are known to regulate circadian rhythms in animals.
  • Limited research exists on this topic in humans.
  • Understanding these rhythms is crucial for gender differences in depression and sleep disturbances during menopause.

Purpose of the Study:

  • To review existing literature on gonadal steroid regulation of circadian rhythms in animals and humans.
  • To propose a hypothesis on estrogen's effects on human circadian rhythms and sleep.
  • To describe an ongoing study investigating these effects in women.

Main Methods:

  • Literature review of animal and human studies.
  • Formulation of a hypothesis regarding estrogen's impact on circadian period, sleep phase, sleep onset, and sleep consolidation.

Related Experiment Videos

  • Description of an ongoing experimental study in women.

    • Main Results:

    • The literature review highlights a significant gap in human research.
    • A hypothesis is proposed: estrogen shortens circadian period, lengthens sleep, advances sleep onset, and consolidates sleep in humans.
    • An ongoing study will test the effects of hypogonadal state, estrogen, and progesterone.

    Conclusions:

    • Gonadal steroids' role in human circadian rhythms requires further investigation.
    • Estrogen may play a significant role in regulating human sleep-activity cycles.
    • The ongoing study aims to provide empirical evidence for these effects in women.